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Immunotherapy and Cervical Cancer

Abstract

Cervical cancer is a leading cause of death worldwide, as per statistical analysis, it is the seventh most common cancer. Majority of the cervical cancers are caused by persistent infections with specific types of the human papillomavirus (HPV). HPV-infected cells produce specific proteins, or antigens that can be recognized by T cells, which are immune cells that play a critical role in the body's response to infectious agents and infected cells. As there are specific targets for development of cervical cancer immunotherapy is emerging as promising treatment for cervical cancer. In this paper we will discuss the target molecules involved in the carcinogenesis and various immunotherapies that are approved and that under clinical trials.

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